Wegovy Pill weight management

Frequently asked questions

• What are oral GLP-1 medications?

  GLP-1 medications mimic a hormone your body releases after eating, one that tells your brain you're full, steadies blood sugar and slows digestion. Once injection-only, they're now available as a daily tablet, like the Wegovy Pill. They work with your biology, helping you feel satisfied with less.

• What's the difference between the Wegovy Pill and the Wegovy injection?

  Both contain semaglutide and work the same way. The injection is once weekly with no timing rules. The pill is daily, first thing on an empty stomach, with a 30-minute wait before eating or drinking. Results are broadly comparable at standard doses.¹ Read the full comparison

• How effective is the Wegovy Pill?

  In the OASIS 4 trial, people taking the 25mg pill daily lost around 16.6% of their body weight over 64 weeks, broadly on a par with the standard injection.² It works best alongside changes to how you eat and move, with support from your Clinician and Health Coach. That's what the CheqUp Method is built around.

• How do I switch from injectable GLP-1s to the pill?

  Switching is possible but needs clinical oversight. Your pill dose depends on your current injection dose and the timing needs careful handling. If you're a CheqUp member, speak to your Clinician through My Account and they'll guide you through it. If you're new to CheqUp, feel free to call our Clinicians for guidance on 0161 570 0287.

• How do I take the Wegovy Pill?

  One tablet first thing every morning with up to 120ml of plain water. Don't break, crush or chew it. Wait at least 30 minutes before eating, drinking anything else or taking other oral medication. You'll start on a low dose, building gradually to 25mg over around 12 weeks. Read the full guide

• How do weight loss tablets work?

  The Wegovy Pill activates the same receptors as your body's natural fullness hormone, reducing appetite and helping you feel satisfied with smaller portions. Unlike older tablets that blocked fat absorption, it addresses the signals that drive hunger in the first place. Read more

• What side effects should I expect?

  The most common are gastrointestinal: nausea, indigestion, constipation, diarrhoea or stomach discomfort. They're most likely in the early weeks and after dose increases, and tend to ease as your body adjusts. If they're making things difficult, your Clinician can help. You don't have to manage this alone.

• Is the Wegovy Pill right for me?

  The pill may suit you if you'd rather not inject and have a consistent morning routine. The injection may be the better fit if you've used semaglutide before, want the highest dose or have a history of cardiovascular disease. Complete a short medical questionnaire and your Clinician will help you choose.